منابع مشابه
Muscles and their myokines.
In the past, the role of physical activity as a life-style modulating factor has been considered as that of a tool to balance energy intake. Although it is important to avoid obesity, physical inactivity should be discussed in a much broader context. There is accumulating epidemiological evidence that a physically active life plays an independent role in the protection against type 2 diabetes, ...
متن کاملExercise-induced myokines and their role in chronic diseases.
Physical inactivity has recently been identified as a major and independent risk factor for the development of dementia and cognitive decline. In addition to the effect of exercise with regard to protection against neurodegenerative diseases, it is well-established that physical inactivity increases the risk of type 2 diabetes, cardiovascular diseases (CVD), colon cancer and postmenopausal brea...
متن کاملConnecting Myokines and Metabolism
Skeletal muscle is the largest organ of the body in non-obese individuals and is now considered to be an endocrine organ. Hormones (myokines) secreted by skeletal muscle mediate communications between muscle and liver, adipose tissue, brain, and other organs. Myokines affect muscle mass and myofiber switching, and have profound effects on glucose and lipid metabolism and inflammation, thus cont...
متن کاملRole of myokines in exercise and metabolism.
During the past 20 yr, it has been well documented that exercise has a profound effect on the immune system. With the discovery that exercise provokes an increase in a number of cytokines, a possible link between skeletal muscle contractile activity and immune changes was established. For most of the last century, researchers sought a link between muscle contraction and humoral changes in the f...
متن کاملSkeletal Muscle, Myokines and Health
Accumulating epidemiological data suggest that a physically active life plays an independent role in the protection against metabolic syndrome, type 2 diabetes, cardiovascular diseases, cancer and dementia. For most of the last century, researchers sought a link between muscle contraction and humoral changes in the form of an 'exercise factor', which could be released from skeletal muscle durin...
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ژورنال
عنوان ژورنال: Journal of Experimental Biology
سال: 2011
ISSN: 1477-9145,0022-0949
DOI: 10.1242/jeb.048074